Catheter Related Bloodstream Infections

Catheter Infections are Frequent, Costly and Deadly

  • 30,000 catheter-line associated bloodstream infections (CLABSIs) occur in dialysis patients annually in the U.S.1
  • Catheters cause 70% of BSIs, yet catheters are used in only 19% of all dialysis procedures1
  • CLABSI is a leading cause for hospitalizations and the second leading cause of death in these patients2
  • The average increased cost of a single CLABSI in a hospital patient is estimated to be between $34,500 – $56,0003

Economic Impact of Bloodstream Infections

  • CLABSIs are a huge problem in hospitals nationally – by example, it is estimated that ~80,000 CLABSIs occur annually in the U.S. in ICUs alone3
  • The average increased cost of a single CLABSI in a hospital patient is estimated to be between ~$34,500 – $56,0003  

How Do ClearGuard HD Caps Reduce Bloodstream Infections?

The ClearGuard HD cap features a rod that extends into the hemodialysis catheter hub. The rod and cap threads are coated with chlorhexidine, a well-known broad-spectrum antimicrobial agent.

  • The antimicrobial coating is activated when inserted into the liquid-filled catheter hub
  • The coating dissolves to kill harmful microorganisms inside the catheter hub
  • The existing catheter clamp holds the antimicrobial agent inside the catheter hub between treatments
  • ClearGuard HD caps are used in place of a standard cap or connector
  • 1Nguyen DB, Shugart A, Lines C, Shah AB, Edwards J, Pollock D, Sievert D, Patel PR: National healthcare safety network (NHSN) dialysis event surveillance report for 2014. Clin J Am Soc Nephrol  12, 1139-1146, 2017
  • 2United States Renal Data System: 2018 USRDS Annual Data Report: End-stage Renal Disease in the United States,Bethesda, MD, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2018
  • 3”Health Care-Associated Infections.” Agency for Healthcare Research & Quality.  April 1, 2015. Accessed January 11, 2016.